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Chunk #19 — Methods — Application of methods — TATES

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A comparison of multivariate genome-wide association methods.
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yes

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TATES [15] (http://ctglab.nl/software) requires a correlation matrix of the traits and univariate association results as input. Full, symmetrical correlation matrices were generated using the corr option in R. UV analyses for the traits were performed by fitting linear models using the lm function in R. TATES was run in R using the freely available script specifying three traits and one genetic variant. The output contains the TATES trait-based p-value corrected for the correlations between the traits, which was extracted for this study.