Chunk #6 — Materials and Methods — SNP selection

Source

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

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Rare variants in OPRM1 were selected from the National Lung Heart and Blood Institute - Exome Sequencing Project (NHLBI-ESP) database (ESP6500 data release), which includes exome sequencing for 6503 European and African American individuals.