The current era of next-generation sequencing deepens the need to investigate the ethical, legal, and social implications associated with genetic testing in AAs, alongside the efforts to encourage greater participation in genetic research. It is essential to balance the potential of new biomedical advances with the ethical and legal structures needed to ensure the protection of human participants involved in research projects.83 This is especially true when working in communities in which there has been an historical misuse of scientific findings, policy implications that adversely affect the community,84 a distrust of some research,85 and concern of group harm.86 The ethical, legal, and social implications surrounding the widely publicized invasion of privacy of Henrietta Lacks and her family as scientists developed the HeLa cell line, shared and sold the HeLa cells without compensation to the family, and published the HeLa genome on the internet, raised public concern, and distrust of genetic research.87
