Saline vs ethanol S-score paraclique networks.(A) Distribution of S-score network sizes based on the number of genes assigned to each. Significantly ethanol-responsive genes were over-represented in a subset of these networks (red bars). (B) These 16 paracliques were considered ethanol-responsive gene-enriched networks (ErGeNs). (C) Network-based clustering of the 1,246 significantly ethanol-responsive genes in the PFC revealed distinct modules largely corresponding to the ErGeNs depicted in B.