< 0.05). In Table 4, twelve flanking SNPs that located near NR4A2 at 2q24.1 have been replicated in the family sample while the top hit was rs1402071 (p = 0.0019). In addition, one SNP rs7624305 near SGOL1 and one SNP rs4947510 within DDC gene revealed borderline significant association with AD in the family sample (p = 0.106 and 0.0916, respectively) (supplementary Table S2).