AUD participants were significantly older [t(49.71)=8.78, p<0.0001], had fewer years of education [t(58)=−7.00, p<0.0001], earlier age of onset of regular alcohol use [t(40)=−4.67, p<0.0001], higher quantity [t(34.57)=5.58, p<0.0001] and frequency [t(39.18)=7.97, p<0.0001] of alcohol use during heavy use period, longer length of abstinence [t(31.97)=3.89, p<0.0005], higher quantity of tobacco use [t(24)=5.19, p<0.0001], and higher frequency of marijuana use [t(11.74)=2.50, p<0.03]. However, the groups did not differ in the quantity of occasional alcohol use and frequency of alcohol and tobacco use during the last six months before participating in the study. Positive correlations between length of abstinence and volumes of bilateral caudate, pallidum, cerebral WM, mid posterior corpus callosum, and total subcortical GM were found, but none of them survived CMT, hence were not reported. Group differences (AUD vs. controls) were evaluated against FWER (α<0.05) based on permutation test-based CMT. Based on FWER, cortical volume measures with p<0.0022 and subcortical volume measures with p<0.0088 were considered significant. Compared to controls, AUD participants had significantly smaller volume in left parsorbitalis [F=10.73, p<0.002], right medial orbitofrontal [F=10.57, p<0.002], right caudal middle frontal cortices
