with BD in our study with previously published results of BD GWA studies. We tested variation at ANK3, which is a candidate gene that was implicated in an earlier GWA study (15) and identified as genome-wide significant in a recent collaborative analysis (17). Finally, we genotyped a subset of SNPs in the regions exhibiting strongest association in a replication case/control group and tracked the co-inheritance of these SNPs and disease in families.
