See Supplemental Material for information regarding study subjects and genotyping and quality control. The final number of BD cases was 1,001 EA subjects and 345 AA subjects; control counts were 1,033 EA subjects and 670 AA subjects. The final dataset consisted of 724,067 SNPs in the EA dataset and 840,730 SNPs in the AA dataset. The two datasets had 702,044 SNPs in common, and these were used to perform analyses addressing SNP and SNPxgenetic background interactions in the combined sample.
