dependence (although the 3% frequency of the G allele in this ethnic group substantially comprises power), while women with the T/T genotype at the rs1799972 polymorphism were found to consume more alcohol [89, 93]. Among Asian populations, the minor allele of A118G was associated with alcoholism in Indian and Japanese cohorts [51, 94]. This association was not observed in studies of Korean or Taiwanese patients, although the G allele did correlate with an increase in the number of drinking days over the course of the study [95-97]. A Meta-analysis of these Asian cohorts confirmed an effect of A118G genotype on susceptibility to alcohol dependence [91].