UCSF Chimera (35) is a 3D protein structure viewer that runs as a web browser helper application on a user’s computer. Once the Chimera application is downloaded and installed, clicking a Chimera link in the Genome Browser will launch the program and display the selected 3D protein structure with all of the non-synonymous SNP residues (identified by LS-SNP/PDB) colored gold and labeled with the dbSNP identifier. When launching Chimera from a SNP track details page, the residue of the selected SNP will be colored red (Figure 2).