A meta-analysis of the discovery and replication PWAS yielded 38 proteins associated with depression at FDR q <0.05 among the 798 proteins that were detected and heritable in both datasets (Supplementary Table 5). Among these 38, 25 were consistent with being causal based on SMR and HEIDI results (Table 3, Supplementary Table 6), and 12 of these proteins were part of the 19 potential causal proteins from the discovery PWAS.
