While depth of inhalation is not directly measured by standard smoking topography, self-reported depth of inhalation was linked to the severity of tobacco-withdrawal symptoms in another study among adolescent smokers [15]. Thus, taken together, as bio-behavioral measures that represent both progression along the addictive cycle and potential correlates of the toxic effects of tobacco smoking constituents, puff topography parameters provide valuable data to predict successful cessation in young established smokers.
