Prevalence rates of experimentation, repeated-use, and SUDs at each wave for each gender are presented in Table 2. At each wave, alcohol was the substance most experimented with, repeatedly used, and abused, while tobacco was the substance with the highest prevalence of dependence. As expected, the prevalence of each category markedly increased between waves of assessment. At Wave 1, there were no significant gender differences overall with respect to each level of substance involvement; however, by Wave 2 a significantly larger proportion of males were involved with most substances.