The primary goal of all quality assurance measures is to generate high quality data. The CoFaMS standard operations manual contains operating procedures for all CoFaMS interview and examination components. Prior to the beginning of CoFaMS-Baseline, the members of the study team underwent an initial training with follow-up quality checks. Performance is closely monitored and routinely assessed. Data management has been carried out in parallel with data collection, based on standardized and partly automated procedures for data processing and plausibility checking. Data backup routines are scheduled on a daily basis.