Chunk #22 — Discussion

Source

Dysregulated postsynaptic density and endocytic zone in the amygdala of human heroin and cocaine abusers.

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Text

The present study reveals disruption of key components of the PSD and coupling to the endocytic zone in the amygdala of human heroin, cocaine and polysubstance heroin-cocaine users that strongly imply disturbances in the regulation of synaptic plasticity.