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Chunk #14 — Results

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ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.
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factors, supports an environmental (i.e. cultural) explanation for the substantially lower rate and magnitude of drinking by women. Additionally, the heritability of maximum drinks and AD in males are 0.49 and 0.46, respectively, but non-significant in females, further reinforcing that, in this population, the proportion of variance in drinking behaviors explained by additive genetic variance is greater in males than in females.