The genes, comprising the significant cis-eQTLs (distance 250 kb, FDR = 0.05), showed an overrepresentation of hydrolase and transferase functions for both datasets, but 'immunity and defense' cis-eQTLs genes were more predominantly detected in the celiac disease peripheral blood dataset than in the HapMap B cell line dataset (see Additional file 2), as might be expected from the differential RNA profiles of the cells under investigation in each dataset.
