that influences lung cancer risk and moreover association between rs401681 risk allele and shorter telomere length has recently been reported(12). High levels of PAH adducts correlate with lung cancer risk and as a major effect of platinum on cells is through adduct formation, CLPTM1L (alias CRR9) is also an attractive lung cancer susceptibility gene as it encodes a transcript whose over-expression has been linked to cis-platinum resistance(13).
