This stage focused both on severely affected methamphetamine dependent subjects and subjects who were methamphetamine-exposed but not dependent (n=589, Table 1). Subjects were hospitalized for four months of residential drug treatment at PMNIDAT from 2015 to 2017. The primary focus of this ongoing study is the genetics of methamphetamine dependence and related traits (including AD). Interviewers were retrained in the SSADDA in 2015 and either certified or re-certified as needed. Additional interviewers hired over the course of the study also underwent standard training. Subjects were administered the SSADDA, and SSADDA quality control procedures were performed, as for Sample 1.
