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Chunk #37 — 4. Discussion

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Linkage scan of alcohol dependence in the UCSF Family Alcoholism Study.
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In conclusion, the current study adds to the literature by supporting evidence of genetic linkage to alcohol dependence for several chromosomal regions. This study also provides evidence suggesting that different chromosomal regions may be associated with alcohol dependence when using the full DSM-IV criteria versus a broader definition of the diagnosis. Finally, the present study provides insight into how distinct genomic regions may underlie different alcohol dependence symptoms and how such data might be used to inform future molecular genetic studies of alcohol dependence.