Chunk #4 — Introduction

Source

Alcohol Use Disorder Polygenic Score Compared With Family History and ADH1B.

Embedded

yes

Text

This study aimed to further increase PGS estimability and test PGS generalizability in populations of European ancestry. We optimized a PGS workflow by using a 2-stage design and included more discovery datasets and target datasets ascertained for different purposes to calculate PGSs and test the best PGS.