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Chunk #21 — 3. RESULTS

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NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.
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This risk region was specific to alcohol dependence in subjects of European descent. It was neither significantly associated with any other non-alcoholism diseases nor alcohol dependence in African-Americans. π0 was less than 0.05 only in the European-American discovery sample (π0=0.037, Table S211).