In conclusion, findings from this study extend knowledge regarding the genetic associations of PTSD and AUD, to include a spectrum of alcohol use phenotypes including more typical alcohol use in an ancestrally diverse population. These findings indicated positive genetic associations between PTSD and alcohol-related problems phenotypes and negative genetic correlations between PTSD and alcohol consumption-related phenotypes. Thus, the genetic factors that may lead someone to develop PTSD and high levels of alcohol consumption are not the same as those that lead someone to develop PTSD and alcohol-related problems. These findings support the growing number of studies demonstrating the important differences regarding risk factors for alcohol consumption v. disorder, and their associations with other psychiatric disorders.
