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Chunk #9 — Introduction

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A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism.
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use parameters and higher sensitivity to the effects of alcohol (a high LR; the opposite of a low LR to alcohol), less drug use and problems, as well as lower indications of externalizing characteristics regarding conduct problems, Novelty Seeking, and Sensation Seeking. Reflecting the finding of Gonçalves et al. (2017), Hypothesis 3 predicted similarities between subjects who recently consumed alcohol above Low-Risk Drinking levels but denied multiple alcohol-related problems and drinkers who admitted to recent alcohol-related difficulties regarding demography, LR, baseline drinking parameters, illicit drug use, Novelty Seeking, and Sensation Seeking. Hypothesis 4 predicted that Abstinence at follow-up would relate to a baseline pattern of older age, more alcohol and drug problems and a higher probability of having received prior AUD-related treatments, with more problems and subsequent treatment associated with the probability that the person will select Abstinence as their way to deal with their AUD. Finally, based on an earlier finding in younger subjects (e.g., Trim et al., 2013), Hypothesis 5 predicted that high LRs would be associated with Low-Risk Drinking and High-Risk Drinking in the absence of multiple alcohol problems, and that low LRs would be associated with multiple alcohol problems and Abstinence in the period before follow-up.