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Chunk #16 — RESULTS

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Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.
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Another noteworthy finding that did not reach GWS was an association with TSNAX-DISC1, SNP rs821722. TSNAX-DISC1 is a read-through transcription between TSNAX (translin-associated factor X) and DISC1 (disrupted in schizophrenia 1). This is the most significant result in the GWAS (meta p = 1.46 × 10−7) of loci with substantial contributions from both the AA (p = 2.12 × 10−5) and EA (p = 3.28 × 10−3) samples (Table S3 in Supplement 2).