Logistic regression examined the relationship of BMI and substance use disorders within each gender separately, after controlling for covariates likely to moderate the relationship of BMI and gender to substance use disorders. In addition, a separate logistic regression assessed the interaction between gender and BMI on substance use disorders in the entire sample, controlling for covariates. Characteristics were included as covariates if they differed significantly across gender and BMI categories or were related to the dependent variable and were likely to contribute to associations between the independent and dependent variables.