the same time, family member Slc2a3 (facilitated glucose transporter) gene expression is decreased (Rodd et al., 2008). Regarding Ntrk2, its gene expression is decreased in the frontal and motor cortices of alcoholics (Mayfield et al., 2002). Moreover, single nucleotide polymorphism (SNP)-based analyses implicate the Ntrk2 gene in alcohol dependence (Xu et al., 2007). The Ntrk2 gene has been implicated in nicotine abuse as well (Beuten et al., 2007; Sun et al., 2007). Several genes responding to glucocorticoid receptor signaling were also altered in the CA versus W groups with 3 genes having reduced expression levels (Fkbp5, Hspa12b, Tsc22d3), whereas only one was increased (Dusp1).
