Among the abstinent smoker groups, there were significant between group differences in VT/fP in the thalamus (F[4,25]=4.12, p=0.011), parietal cortex (F[4,25]=2.95, p=0.040), frontal cortex (F[4,25]=2.88, p=0.043), anterior cingulate (F[4,25]=3.75, p=0.016), occipital cortex (F[4,25]=3.42, p=0.023), and cerebellum (F[[4,25]=4.00, p=0.012). Compared to 1 week abstinent smokers, 1 day abstinent smokers had significantly lower VT/fP in the thalamus (t[25]=-3.51, corrected p=0.007) and cerebellum (t[25]=-3.02, corrected p=0.023). Compared to 1 week abstinent smokers, 6-12 week abstinent smokers had significantly lower VT/fP in the parietal cortex (t[25]=-2.87, corrected p=0.033), frontal cortex (t[25]=-2.80, corrected p=0.039), anterior cingulate (t[25]=-3.21, corrected p=0.014), occipital cortex (t[25]=-3.10, corrected p=0.019) and cerebellum (t[25]=-3.17, corrected p=0.016). There were no significant differences in VT/fP between 1 week abstinent smokers compared to smokers at 2 or 4 weeks of abstinence (Table 3 and Figures 1 and 2).
