Regional β2*-nAChR availability, reflected by VT/fP, was compared between nonsmokers and each of the abstinent smoker groups and between the abstinent smoker groups (Table 3 and Figures 1 and 2). In 1 day abstinent smokers as compared to nonsmokers, VT/fP was significantly reduced in the thalamus. In 1 week abstinent smokers as compared to nonsmokers, VT/fP was significantly higher in the striatum, cerebellum and throughout the cortex. In 4 week abstinent smokers as compared to nonsmokers, VT/fP was significantly higher in the occipital cortex (Table 3 and Figures 1 and 2).
