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Chunk #6 — Results — GWAS meta-analysis identifies 30 genome-wide significant loci

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Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
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cell countrs493120q13.125.00 × 10−80.96090.0073C/A0.2780.2790.9935Blood cell count, height, BMIShown are the lead SNP, the chromosome, base pair position on the genome, P value, effect estimate as an odds ratio (OR), s.e., effect allele and non-effect allele (A1 and A2), frequency of A1 in cases (FRQCA) and in controls (FRQCO), imputation quality score (INFO), number of genes in a region of 6.5 kb around the SNP (n genes) and a curated list of phenotypes that also showed a genome-wide significant association with this SNP (in one or more of the following four databases: CAUSALdb90, GenomeAtlas52, the NHGRI-EBI GWAS Catalog91, the IEU Open GWAS project92). If fewer than four traits are significant across all four databases, all four traits are shown. If more than five traits are significant across the databases, neuropsychiatric traits are prioritized (closely related traits are summarized into one trait category). For a full list of associations in the four databases, see Supplementary Table 18a–d. A more detailed list of the significant loci can be found in Supplementary Table 2. Abbreviations in the last column are SCZ, schizophrenia; BP, bipolar disorder; MDD, major depressive disorder; UV, ultraviolet. aPreviously identified GWAS hits for OCD (or SNPs in high linkage disequilibirum with