DISC1 gene (P < 0.006), and rs10089 predicts the expression of an expressed sequence in the 5’ region of the NKCC1 gene (P < 0.02). Thus, each of these SNPs, which interact to affect risk for schizophrenia, is associated with variable expression of their respective transcripts in the human brain. These data add to the evidence that these SNPs are marking functional domains within the gene that impact gene function.
