In this study, we performed a GWAS on two smoking-related behaviors, SI and ND, in a cohort from the Korea Association Resource (KARE) project (Cho et al. 2009). A total of 8,842 individuals with 352,228 SNPs genotyped per individual were examined to find any association between smoking behavior and genetic factors. Our initia analysis at the discovery stage identified 12 SNPs (p < 1 × 10−5) significantly associated with smokin behavior. Although they did not reach the genome-wid significance level (p < 1 × 10−7), they represented severa genomic regions possibly associated with smoking behavior. Among 12 SNPs, 8 were significantly associated with SI and 4 with ND.
