leveraging the power of additional large-scale GWAS. Furthermore, the impact of the ELOVL7 skipped exon in the brain was visualized by association analysis with magnetic resonance imaging data from the UK Biobank. Predicted downstream genes and biological pathways of the replicated splicing events implicated immunological and neurological functions. The framework presented here is broadly applicable to study the role of RNA splicing in the heritability of complex disease.
