Despite overall declines in the prevalence of adult cigarette smoking, prevalence remains high among certain subpopulations, particularly persons with mental illness (1). Research suggests that smoking prevalence among U.S. adults with mental illness or serious psychological distress ranges from 34.3% (phobias or fears) to 88% (schizophrenia), compared with 18.3% among adults with no such illness (2,3). Persons with mental illness might smoke more frequently and heavily than the general population (2), and they might lack access to cessation services (4,5). Monitoring tobacco use across all sub-populations† is necessary to meet the Healthy People 2020 target of reducing the prevalence of cigarette smoking among adults to ≤12% (objective TU-1).§ Using data from the 2009–2011 National Survey on Drug Use and Health (NSDUH), this report provides the most recent national and state estimates of cigarette smoking among adults aged ≥18 years with AMI.