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Chunk #20 — RESULTS — Genome-wide Association in the Australian Sample

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A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.
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The lowest p-values for ND, AD and comorbid AD/ND respectively were 4.43×10−8 (rs964170 in ARHGAP10 on chromosome 4), 3.91×10−7 (rs12761801 in CTBP2 on chromosome 10) and 1.91×10−9 (rs7530302 located in a region upstream of MARK1 on chromosome1), with two additional SNPs for comorbid AD/ND (rs1784300 near DDX6 on chromosome 11 and rs12882384 in KIAA1409 on chromosome 14) giving p-values less than 5×10−8. Tables 3, 4, and 5 list detailed results for the 30 SNPs with lowest p-values from the analysis of the ND, AD and comorbid AD/ND DNA pools in the Australian sample.