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Chunk #27 — Discussion

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Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.
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A total of 13 markers in the present study reached a value of p<1E–5, including rs1789891. Of the seven variants that are not located at the ADH1C locus, four SNPs are located in genes (see Table 1; for functional annotation of these genes see supporting Table S1).