Manhattan plots and quantile-quantile plots depicting SNP effects on the components of the model are included in Figure 3 and Figure 4. In adolescence, three SNPs met the threshold for genome-wide significance of p<5e-8 (rs116734991, rs115778926, rs117048287). Note that these SNPs have not been detected in previous, larger GWAS of alcohol use outcomes. An additional 32 SNPs met the suggestive threshold of p<1e-5 in adolescence. No SNPs reached genome-wide significance in the other GWAS. In early adulthood, 67 SNPs met the suggestive threshold. In adulthood, 38 SNPs met the suggestive threshold. In the common factor GWAS, 30 SNPs met the suggestive threshold. Lists of all SNPs meeting these thresholds in adolescence, early adulthood, adulthood and the common factor are available in Table S4, Table S5, Table S6, and Table S7.
