The resulting genetic data and clinical data were analyzed using the JMP suite of programs (SAS Institute, Cary, USA) and the test subroutines described in the text or in the tables. As described above, Hardy-Weinberg equilibrium for each SNP was examined using Chi square analysis with a cut off value of p<0.01). Haplotype and genotype were analyzed using an additive model. Clinical syndrome symptom counts were treated as ordinal variables. All p-values reported are those using a two-tailed test.
