The cross-generational THC animal model has been described in detail previously (Szutorisz et al, 2014). Briefly, adolescent male and female Long-Evan rats were administered THC (1.5 mg/kg every third day from postnatal day 28–49) or VEH. Animals were mated as adults when no detectable THC was present and their pups were raised by drug-naïve mothers (see Supplementary Materials and Materials and Methods for more details).
