Chunk #13 — Do cannabinoids cause short-lived positive psychotic symptoms, negative symptoms and cognitive deficits in the general population? — Experimental evidence
mild euphoria to more pronounced reactions, including feelings of loss of self-control and body distortion suggestive of psychotic-like symptoms. One subject experienced a transient psychotic episode described as “a paranoid psychotic state with persecutory delusions, delusions of thought insertion, attentional irritability, fear, and—to some extent—verbal aggressive behavior.” However, this study was not placebo-controlled. In a subsequent study with nabilone, a synthetic analog of Δ9-THC, Leweke et al. [127] observed that nabilone produced effects on binocular depth inversion that were similar to Δ9-THC.
