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Chunk #25 — Methods — Statistical analyses

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Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy.
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In a case/control division of subjects based on presence or absence of cocaine use disorder, logistic regressions were run both using as controls only those who had been exposed to cocaine but had not become dependent (i.e. have used cocaine at least once in their lifetime) and all non-cocaine-dependent individuals in the sample, regardless of exposure status.