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Chunk #33 — Methods — Study population

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Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
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muscular tension are evaluated in this instrument by the patients in the terms of none (1) a little (2), moderate (3) or severe disturbance (4). The numbers are then transcribed as occurrence between 0-100% as described in the above reference. The study was performed in compliance with the Helsinki Declaration and the regional Ethical Review Board in Uppsala approved the study. All patients and controls signed a written informed consent.