For datasets not participating in the Repository, we cannot overcome obstacles (1)-(4). However, for researchers who wish to construct the PGIs in a non-participating dataset, we facilitate this effort by posting on the SSGAC website (www.thessgac.org/data) the weights underlying the PGIs constructed from publicly available data (i.e., that have no 23andMe data). As mentioned above, we also post the code we used for constructing the PGIs and PCs (https://www.thessgac.org/pgi-repository). In addition, we refer researchers to 23andMe’s “Publication Dataset Access Request Form” (https://research.23andme.com/dataset-access/#how-to), which allows researchers to gain access to GWAS results used in published papers (after signing a Data Use Agreement with 23andMe). In this way, researchers can gain access to the same 23andMe data that we used, and use it to construct the PGIs that are wholly or partly based on data from 23andMe.
