Here, our aim was to conduct the first GWAS in a cohort of prisoners fulfilling the diagnostic criteria of ASPD according to DSM-IV as compared to controls from the general population, and to replicate the most significant findings in another set of prisoners and controls. We then searched for the impact of the identified genetic risk for ASPD for antisocial features and its interaction with childhood risk environment in the general population. Finally, we investigated the functional implication of the risk variations for ASPD by searching for their correlations to gene expression in human tissue databases.
