Chunk #8 — METHODS — MEASURES — Substance dependence and remission

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Probability and predictors of remission from life-time nicotine, alcohol, cannabis or cocaine dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

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Early substance use onset (defined as before age 14) and family history of SUDs (any alcohol or drug use disorder among first degree relatives) were also included as substance use-related covariates. The good to excellent (κ=0.54–0.91) test-retest reliability and validity of AUDADIS-IV SUD diagnoses is well documented in clinical and general population samples [21–24].