The continuous expansion of the JASPAR database provides TF binding profiles for an increasing number of TFs from different organisms. With this release, the JASPAR CORE vertebrates collection presents a motif for 53% of the 1435 curated human TFs (58% of the 1118 orthologous mouse TFs) (2), 67% (64% of mouse orthologs) when adding profiles from the UNVALIDATED collection. The JASPAR CORE plants collection presents profiles for 32% of the 1717 reported A. thaliana TFs (42), 35% when including profiles from the UNVALIDATED collection. Another example is the JASPAR CORE insects collection, which provides a motif for 43% of the 628 TFs reported for D. melanogaster (43) and 50% when including UNVALIDATED profiles. A steady effort from the community to cover all TFs will be necessary to fill the remaining gap.
