et al. 2007 b).rs412050235.83E-0622q11.2220637519Immediately downstream of PPM1F The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. Expressed in brain and other tissues. Finding lies in linkage region for schizophrenia from meta-analysis (Lewis et al. 2003) and close to linkage finding for smoking (Saccone et al. 2007)Site known for CNVsrs515910244.36E-0610q25.1105956394In intron of C10orf79 Gene/protein of unknown function expressed in brain and other tissuesrs220470281.34E-0717p13.23611724 ITGAE Encodes integrin alpha E. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Expressed in multiple tissues including brain. Finding lies within linkage region for ADHD from meta-analysis (Zhou et al. 2008c)Also lies within suggestive linkage region for ADHD reported in the same publication (Lesch et al. 2008). Another integrin alpha, encoded by ITGA11, also is listed at rank 50rs4964805324.74E-0612q23.3102716954In intron of NT5DC3 Encodes 5′-nucleotidase domain containing 3, a potential oncogene. Expression is found in brain and several other tissues. Finding lies close to linkage regions for the personality trait neuroticism (Fullerton
