paperKB
coga / coga-kb
Help
Sign in

Chunk #14 — Subjects and methods — Statistical analysis — Heritability analyses — Multivariate models

Source
Heritability of obsessive-compulsive trait dimensions in youth from the general population.
Embedded
yes

Text

We tested the degree to which A, C, and E factors accounted for the co-variance between the OC trait dimensions for the TOCS. We fit a multivariate correlated factor model to test the assumption that each pair of OC trait dimensions is directly influenced by genetic (A) and environmental (C and E) variance components that are correlated. A correlation between the A variance components of two OC trait dimensions was interpreted as an indication of a shared genetic influence (i.e., the genetic factors that explain variation in the first OC trait dimension explain a proportion of the variation in the second OC trait dimension). A correlation between the C or E variance components was interpreted as an indication of overlapping environmental influences (i.e., the environmental factors that explain variation in the first OC trait dimension explain a proportion of the variation in the second OC trait dimension). A genetic or environmental correlation of zero between two OC trait dimensions would indicate independence in the variance components explaining the variation in those two dimensions.