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Chunk #16 — 2. METHODS — 2.3 Statistical Analyses

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Genetic etiology of the common liability to drug dependence: evidence of common and specific mechanisms for DSM-IV dependence symptoms.
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Extensions of the classical twin model are useful for decomposing the variance and covariance between observed traits into their genetic and environmental components. Typical models used to resolve the covariance of multiple phenotypes are the Independent Pathway model and the Common Pathway model (Neale and Cardon, 1992).