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Chunk #35 — GxE Studies Using Measured Genotypes — Genotypic Moderation of Environmental Risk — Monoamine Oxidase A Gene

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The influence of gene-environment interactions on alcohol consumption and alcohol use disorders: a comprehensive review.
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2.0) and those without exposure to psychosocial adversity (median = 2.0 and 0.0, respectively, among those homozygous for the high-activity variant and carriers of the low-activity variant) (Nilsson, Wargelius, Sjöberg, Leppert, & Oreland, 2008). In a sample of American Indian adult women, Ducci et al. (2008) found that CSA was associated with greater risk for AUDs (particularly antisocial AUDs) among women with two copies of the low-activity MAOA variant compared to those with one or two copies of the high-activity variant.